Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Noise versus resolution plots (a) at the CFOV and (b) at 8 mm offset for 2D-FBP, 2D-OSEM, and 3D-MAP with various β values.

Article Snippet: Methods: The authors present an evaluation of the quantitative accuracy of the 3D maximum a posteriori (3D-MAP) image reconstruction algorithm for dynamic PET imaging with comparisons to two of the most widely used reconstruction algorithms: the 2D filtered-backprojection (2D-FBP) and 2D-ordered subsets expectation maximization (2D-OSEM) on the Siemens microPET scanners.

Techniques:

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Activity concentration ratio between spheres and surrounding background area for (a) 2D-FBP, (b) 2D-OSEM, (c) 3D-MAP β = 0, (d) 3D-MAP β = 0.01, (e) 3D-MAP β = 0.1 and (f) 3D-MAP β = 0.5) with various scan durations. Error bars indicate statistical uncertainty over the different realizations. A ratio of 10.11 indicates complete recovery of the activity. The count densities in the background area were multiplied by 10 for this presentation.

Article Snippet: Methods: The authors present an evaluation of the quantitative accuracy of the 3D maximum a posteriori (3D-MAP) image reconstruction algorithm for dynamic PET imaging with comparisons to two of the most widely used reconstruction algorithms: the 2D filtered-backprojection (2D-FBP) and 2D-ordered subsets expectation maximization (2D-OSEM) on the Siemens microPET scanners.

Techniques: Activity Assay, Concentration Assay

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Activity concentration of the spheres filled with 11C and background area filled with 18F solution plotted as a function of time for (a) 2D-FBP and (b) 3D-MAP (20 iterations and β = 0.05).

Article Snippet: Methods: The authors present an evaluation of the quantitative accuracy of the 3D maximum a posteriori (3D-MAP) image reconstruction algorithm for dynamic PET imaging with comparisons to two of the most widely used reconstruction algorithms: the 2D filtered-backprojection (2D-FBP) and 2D-ordered subsets expectation maximization (2D-OSEM) on the Siemens microPET scanners.

Techniques: Activity Assay, Concentration Assay

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Transverse and coronal images of the mouse myocardial phantom filled with 11C and reconstructed with (a)–(b) 2D-FBP and (c)–(d) 3D-MAP (20 iterations, β = 0.05).

Article Snippet: Methods: The authors present an evaluation of the quantitative accuracy of the 3D maximum a posteriori (3D-MAP) image reconstruction algorithm for dynamic PET imaging with comparisons to two of the most widely used reconstruction algorithms: the 2D filtered-backprojection (2D-FBP) and 2D-ordered subsets expectation maximization (2D-OSEM) on the Siemens microPET scanners.

Techniques:

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: (a) The MAP gated image showing the small ROI traced inside the left ventricle of a mouse injected with 0.5 mCi (18.5 MBq) of 18F-FDG. (b) Blood activity concentrations derived from the ROI shown in (a). Images were reconstructed with 2D-FBP and 3D-MAP (20 iterations, β = 0.05). EKG data (at diastole) are also presented.

Article Snippet: Methods: The authors present an evaluation of the quantitative accuracy of the 3D maximum a posteriori (3D-MAP) image reconstruction algorithm for dynamic PET imaging with comparisons to two of the most widely used reconstruction algorithms: the 2D filtered-backprojection (2D-FBP) and 2D-ordered subsets expectation maximization (2D-OSEM) on the Siemens microPET scanners.

Techniques: Injection, Activity Assay, Derivative Assay

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Noise versus resolution plots (a) at the CFOV and (b) at 8 mm offset for 2D-FBP, 2D-OSEM, and 3D-MAP with various β values.

Article Snippet: The 3D maximum a posteriori (3D-MAP) algorithm 3 distributed with the Siemens PreClinical Solution microPET cameras is such an algorithm and implements these corrections (with the exception of the positron range correction).

Techniques:

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Activity concentration ratio between spheres and surrounding background area for (a) 2D-FBP, (b) 2D-OSEM, (c) 3D-MAP β = 0, (d) 3D-MAP β = 0.01, (e) 3D-MAP β = 0.1 and (f) 3D-MAP β = 0.5) with various scan durations. Error bars indicate statistical uncertainty over the different realizations. A ratio of 10.11 indicates complete recovery of the activity. The count densities in the background area were multiplied by 10 for this presentation.

Article Snippet: The 3D maximum a posteriori (3D-MAP) algorithm 3 distributed with the Siemens PreClinical Solution microPET cameras is such an algorithm and implements these corrections (with the exception of the positron range correction).

Techniques: Activity Assay, Concentration Assay

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Activity concentration of the spheres filled with 11C and background area filled with 18F solution plotted as a function of time for (a) 2D-FBP and (b) 3D-MAP (20 iterations and β = 0.05).

Article Snippet: The 3D maximum a posteriori (3D-MAP) algorithm 3 distributed with the Siemens PreClinical Solution microPET cameras is such an algorithm and implements these corrections (with the exception of the positron range correction).

Techniques: Activity Assay, Concentration Assay

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: Transverse and coronal images of the mouse myocardial phantom filled with 11C and reconstructed with (a)–(b) 2D-FBP and (c)–(d) 3D-MAP (20 iterations, β = 0.05).

Article Snippet: The 3D maximum a posteriori (3D-MAP) algorithm 3 distributed with the Siemens PreClinical Solution microPET cameras is such an algorithm and implements these corrections (with the exception of the positron range correction).

Techniques:

Journal: Medical Physics

Article Title: Quantitative accuracy of MAP reconstruction for dynamic PET imaging in small animals

doi: 10.1118/1.3678489

Figure Lengend Snippet: (a) The MAP gated image showing the small ROI traced inside the left ventricle of a mouse injected with 0.5 mCi (18.5 MBq) of 18F-FDG. (b) Blood activity concentrations derived from the ROI shown in (a). Images were reconstructed with 2D-FBP and 3D-MAP (20 iterations, β = 0.05). EKG data (at diastole) are also presented.

Article Snippet: The 3D maximum a posteriori (3D-MAP) algorithm 3 distributed with the Siemens PreClinical Solution microPET cameras is such an algorithm and implements these corrections (with the exception of the positron range correction).

Techniques: Injection, Activity Assay, Derivative Assay